Well if you have had the pleasure of changing a 6.0 Diesel fuel filter, you know that on the F series it can be a bit messy.  A quick tip to make life easier is to remove the fuel drain plug.  This is useful in draining the housing as well a removing any water or debris from the primary fuel filter assembly along the frame.  There is a hex plug located in the middle of the assembly towards the bottom.  It will be partially blocked if you own a 4x4, but an allen wrench will remove the plug.  Don't loose the sealing washer.  Pull the plug, catch the fuel and any debris that comes with it.  Less mess and your shirt won't smell like diesel fuel the rest of the day.